Chlojaponilactone B is a lindenane-type sesquiterpenoid with anti-inflammatory properties. Chlojaponilactone B suppresses inflammatory responses by inhibiting TLR4 and subsequently decreasing reactive oxygen species (ROS) generation, downregulating the NF-kappaB, thus reducing the expression of the pro-inflammatory cytokines iNOS, NO, COX-2, IL-6 and TNF-alpha[1].
Molecular Weight:
286.32
Purity:
98
CAS Number:
[1449382-91-5]
Formula:
C17H18O4
Target:
NF-kappaB,Reactive Oxygen Species (ROS),Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Natural Products
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