Neriifolin, a CNS-penetrating cardiac glycoside, is an inhibitor of the Na+, K+-ATPase. Neriifolin can target beclin 1, inhibits the formation of LC3-associated phagosomes and ameliorates experimental autoimmune encephalomyelitis (EAE) development. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells[1][2.
Molecular Weight:
534.68
Purity:
99.70
CAS Number:
[466-07-9]
Formula:
C30H46O8
Target:
Apoptosis,Atg8/LC3,Beclin1,Na+/K+ ATPase
Application Notes:
MCE Product type: Natural Products
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