Cryogenine is an alkaloid originally isolated from H. salicifolia that has anti-inflammatory activity. It inhibits prostaglandin synthetase (IC50=424 µM). Cryogenine (100 mg/kg per day, p.o.) reduces paw edema and the mean arthritic index in a rat model of adjuvant-induced polyarthritis.
Molecular Weight:
435.51
CAS Number:
[10308-13-1]
Formula:
C26H29NO5
Target:
PGE synthase
Application Notes:
MCE Product type: Natural Products
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