Myrothecine A, CAS [[910292-40-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N8508
Supplier Catalog Number:
HY-N8508
Alternative Catalog Number:
MCE-HY-N8508-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Myrothecine A is a trichothecene mycotoxin found in M. roridum. Myrothecine A induces apoptosis, promotes the cytochrome c release, PARP-cleavage and phosphorylation of JNK, increases Bax and cleaved caspase-3, -5, and -8 levels. Myrothecine A has anticancer activities and promotes the maturation of DC cells in the microenvironment. Myrothecine A inhibits proliferation of A549, MCF-7, HepG2, and SMMC-7721 cancer cells with IC50s of 95, 70, 60, and 25 µM, respectively[1][2][3].
