Malabaricone C is an orally active and noncompetitive sphingomyelin synthase (SMS) inhibitor with IC50 values of 3 µM and 1.5 µM for SMS 1 and SMS 2, respectively. Malabaricone C reduces body weight gain, improves glucose tolerance, and decreases lipid accumulation in the liver, showing significant prevention of high fat diet-induced fatty liver in mice. Malabaricone C has anti-inflammatory effects, which is found in the fruits of Myristica cinnamomea King. Malabaricone C is promising for research of obesity and immunological disorders caused due to hyper-activation of T-cells[1][2][3].
Molecular Weight:
358.43
Purity:
99.46
CAS Number:
[63335-25-1]
Formula:
C21H26O5
Target:
Apoptosis,NF-kappaB,p38 MAPK,Phospholipase
Application Notes:
MCE Product type: Natural Products
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