Degalactotigonin, CAS [[39941-51-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N9684
Supplier Catalog Number:
HY-N9684
Alternative Catalog Number:
MCE-HY-N9684-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Degalactotigonin is a saponin-selective inhibitor targeting the EGFR, GSK3beta and Hedgehog/Gli1 pathways and can be isolated from Solanum nigrum (Solanum nigrum). Degalactotigonin inhibits EGFR phosphorylation and the downstream Akt/ERK signaling pathway, and at the same time inhibits the Hedgehog/Gli1 pathway through GSK3beta inactivation, thereby inducing cancer cell apoptosis, arresting the cell cycle, and inhibiting migration and invasion. Degalactotigonin can be used in targeted research on malignant tumors such as pancreatic cancer and osteosarcoma[1][2].
Molecular Weight:
1035.17
CAS Number:
[39941-51-0]
Formula:
C50H82O22
Target:
Akt,Apoptosis,EGFR,ERK,GSK-3,Hedgehog
Application Notes:
MCE Product type: Natural Products
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