Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R (Ki: 40 nM). Nonapeptide-1 is a competitive alpha-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by alpha-MSH in melanocytes (IC50: 2.5 nM and 11 nM, respectively). Nonapeptide-1 inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer[1][2][3].
Molecular Weight:
1206.50
Purity:
99.04
CAS Number:
[158563-45-2]
Formula:
C61H87N15O9S
Target:
Melanocortin Receptor
Application Notes:
Peptides
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