Tat-NR2B9c, CAS [[500992-11-0]]

Product Overview

• Article Name: Tat-NR2B9c, CAS [[500992-11-0]]
• Biozol Catalog Number: MCE-HY-P0117
• Supplier Catalog Number: HY-P0117
• Alternative Catalog Number: MCE-HY-P0117-10MG, MCE-HY-P0117-5MG, MCE-HY-P0117-25MG, MCE-HY-P0117-1MG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: Tat-NR2Bct, NA-1

Product Description

Tat-NR2B9c (Tat-NR2Bct, NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 µM and 8 µM, respectively. Tat-NR2B9c also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy[1][2][5].

Product Properties

• Molecular Weight: 2518.88
• Purity: 99.77
• CAS Number: [500992-11-0]
• Formula: C105H188N42O30
• Target: iGluR,NO Synthase

Application Notes

• Application Notes: Peptides