Apoptin-derived peptide acetate is an antitumor polypeptide with cytotoxicity. Apoptin-derived peptide acetate promotes apoptosis and necroptosis of gastric cancer (GC) cells by regulating PI3K/AKT/ARNT signaling. Apoptin-derived peptide acetate inhibits the invasion and migration of cancer cells, and inhibits the expression and phosphorylation of the subunit p85 of PI3K, which further inhibits the PI3K/AKT pathway involved in the development of gastric cancer[1].
Molecular Weight:
5177.33 (free base)
Purity:
98.30
Formula:
C223H417N89O50SxC2H4O2
Target:
Akt,Apoptosis,Necroptosis,PI3K
Application Notes:
MCE Product type: Peptides
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