Cyclic AC253 is an antagonist for amylin receptor, with IC50 of 0.3 µM. Cyclic AC253 exhibits neuroprotective efficacy against Abeta toxicity and abrogates Abeta-induced impairment of hippocampal long-term potentiation. Cyclic AC253 penetrate blood-brain barrier (BBB)[1].
Molecular Weight:
3009.34
Purity:
99.83
Formula:
C126H202N42O40S2
Target:
Amylin Receptor
Application Notes:
MCE Product type: Peptides
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