ATR kinase substrate peptide (compound 45) is a potent and selective inhibitor of ATR (Ataxia Telangiectasia and Rad3 related) protein kinase (Ki=6 nM). ATR kinase substrate peptide inhibits ATR activity by competing with ATR kinase ATP-binding sites to block ATR mediated signaling. ATR kinase substrate peptide can be used to study the role of ATR kinase in DNA damage response[1].
Molecular Weight:
1814.05
Purity:
99.17
Formula:
C81H132N22O25
Target:
ATM/ATR
Application Notes:
MCE Product type: Peptides
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