Serpinin is an agonist of the protease inhibitor Nexin-1 (PN-1). Serpinin upregulates the expression of PN-1 through the cAMP-PKA-Sp1 signaling pathway, promoting granule biogenesis in endocrine cells. Serpinin is used in research related to the regulation of secretory function[1]. Serpinin is a selective agonist for beta-adrenergic receptors. Serpinin interacts with beta1-adrenergic receptors to activate the AC-cAMP-PKA pathway, which regulates myocardial systolic and diastolic function. pGlu-serpinin upregulates Bcl2 mRNA transcription and exerts neuroprotective effects[2].
Molecular Weight:
2891.14
Purity:
98.74
CAS Number:
[1383743-23-4]
Formula:
C125H204N32O46
Target:
Serpin
Application Notes:
MCE Product type: Peptides
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