RSM3 is a METTL3-METTL14 complex inhibitor with a Kd of 3.10 µM for the METTL3-METTL14 complex. RSM3 reduces the m6A modification level of SLC31A1 and the global RNA methylation level. RSM3 upregulates programmed cell death-related genes, enhances cell apoptosis, inhibits pro-cancer signals and suppresses tumor growth. RSM3 is applicable to the research of preeclampsia and cancer[1][2].
Molecular Weight:
3049.66
Purity:
95.73
Formula:
C130H218N54O26S3
Target:
Apoptosis,Caspase,MDM-2/p53,METTL3,NF-kappaB
Application Notes:
MCE Product type: Peptides
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