PDpep1.3 is a peptide inhibitor of alpha-synuclein that disrupts the direct interaction between alpha-synuclein and CHarged Multivesicular body Protein 2B (CHMP2B). As a result, PDpep1.3 restores the degradation function of endosomes and lysosomes, reduces the protein level and aggregation of alpha-synuclei, and protects dopaminergic neurons from alpha-synuclei-mediated degeneration. PDpep1.3 can be used to study neurodegenerative diseases and protein-protein interactions[1].
Molecular Weight:
1400.53
CAS Number:
[2942277-55-4]
Formula:
C59H101N17O22
Target:
alpha-synuclein
Application Notes:
MCE Product type: Peptides
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