A11 (acetate)

Catalog Number: MCE-HY-P10412A
Article Name: A11 (acetate)
Biozol Catalog Number: MCE-HY-P10412A
Supplier Catalog Number: HY-P10412A
Alternative Catalog Number: MCE-HY-P10412A-5MG,MCE-HY-P10412A-25MG,MCE-HY-P10412A-1MG,MCE-HY-P10412A-10MG
Manufacturer: MedchemExpress
Category: Proteine/Peptide
A11 (ANXA1-derived 11 amino acid-long peptide) acetate is an ANXA1-EphA2 interaction blocker peptide. A11 acetate decreases ANXA1 bound to EphA2 and increased Cbl (an E3 ubiquitin ligase of EphA2) bound to EphA2. A11 efficiently decreases EphA2 level, and substantially increases EphA2 ubiquitination. A11 acetate increases EphA2 internalization and colocalization of EphA2 and Cbl in the NPC cells. A11 acetate inhibits nasopharyngeal carcinoma (NPC) cell proliferation, migration and invasion. A11 acetate inhibits angiogenesis[1].
Molecular Weight: 2767.16 (free base)
Purity: 98.48
Formula: C117H204N46O32.xC2H4O2
Target: Ephrin Receptor
Application Notes: MCE Product type: Peptides