EPI-X4 (hSA408-423 peptide) is an antagonist for C-X-C motif chemokine receptor 4 (CXCR4) with IC50 of 8.6 µM. EPI-X4 blocks the CXCL12-mediated signaling, inhibits chemokine-mediated migration and invasion of leukemia cell. EPI-X4 exhibits anti-inflammatory activity in mouse model. EPI-X4 exhibits antiviral activity against CXCR4-tropic HIV with IC50 of 8.6 µM[1].
Molecular Weight:
1830.18
Purity:
99.21
CAS Number:
[930280-31-2]
Formula:
C84H144N22O23
Target:
CXCR
Application Notes:
Peptides
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