CVRARTR is a programmed cell death ligand-1 (PD-L1) antagonist with a KD of 281 nM. CVRARTR induces the internalization of PD-L1 and downregulates PD-L1 on the cell surface. CVRARTR restores cytokine secretion and T cell proliferation in cell CT26. CVRARTR exhibits antitumor efficacy against in CT26 homograft mouse model. CVRARTR can be used in melanoma research[1][2].
Molecular Weight:
861.03
Purity:
99.26
CAS Number:
[2349354-64-7]
Formula:
C33H64N16O9S
Target:
PD-1/PD-L1
Application Notes:
Peptides
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