KZR-8445 TFA is a Sec61 inhibitor. KZR-8445 TFA disrupts the biosynthesis of secretory and membrane proteins. KZR-8445 TFA inhibits the secretion of proinflammatory cytokines in primary immune cells. KZR-8445 TFA blocks the replication of SARS-CoV-2, virus-induced cytotoxicity, and the biosynthesis of spike protein. KZR-8445 TFA blocks disease progression in a mouse model of rheumatoid arthritis with good tolerance and no obvious toxicity. KZR-8445 TFA can be used in the research of diseases such as rheumatoid arthritis and viral infection[1].
Molecular Weight:
1197.98
Formula:
C51H62BrF9N8O10
Target:
Interleukin Related,SARS-CoV,Sec61
Application Notes:
MCE Product type: Peptides
* VAT and and shipping costs not included. Errors and price changes excepted
