NBD-2 is an inhibitor of the NEMO-IKKalpha/beta interaction in the NF-kappaB signaling pathway. NBD-2 specifically inhibits the typical NF-kappaB signaling pathway in vitro and in vivo, reducing the inflammatory response in lipopolysaccharide (LPS) induced acute lung injury (ALI). NBD-2 exhibits significant anti-inflammatory activity. NBD-2 can be used to study diseases related to NF-kappaB signaling pathway, including autoimmune diseases, cancer, etc[1].
Molecular Weight:
1647.66
Formula:
C73H86F8N14O17S2
Target:
NF-kappaB
Application Notes:
Peptides
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