Brevicidine TFA is an antimicrobial peptide with selective bactericidal activity against Gram-negative pathogens. Brevicidine TFA disrupts bacterial morphology by binding to lipopolysaccharide (LPS) on the bacterial cell membrane to form pores. Brevicidine TFA causes dissipation of intracellular proton motive force, outer membrane damage, inhibition of ATP biosynthesis and reactive oxygen species accumulation in bacterial cells. As a sensitizer, Brevicidine TFA exerts synergistic activity when combined with a variety of conventional antibiotics[1][2].
Molecular Weight:
1519.74 (free base)
Purity:
97.81
Formula:
C74H106N18O17xC2HF3O2
Target:
Bacterial,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Peptides
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