(RXR)4XB is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC50 of 0.5 to 16 µM, and reduces the bacterial burden in mouse acute pneumonia models[1].
Molecular Weight:
1904.37
CAS Number:
[879010-15-8]
Formula:
C81H158N38O15
Target:
Bacterial
Application Notes:
Peptides
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