Macrophage-activating lipopeptide 2 TFA is an agonist of Toll like receptors TLR-2/TLR-6. Macrophage-activating lipopeptide-2 enhances endothelial nitric oxide synthase (eNOS) phosphorylation and endothelial cell release of NO, thereby improving vasodilation. Macrophage-activating lipopeptide-2 enhances endothelial adhesion of white blood cells and improve perfusion recovery and collateral growth in the hind limbs of hypercholesterolemic Apoe deficient mice undergoing experimental femoral artery ligation (FAL)[1].
Molecular Weight:
2135.56 (free base)
Purity:
98.60
Formula:
C99H167N19O30S.xC2HF3O2
Target:
NO Synthase,Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Peptides
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