Apelin-36(human) is an endogenous orphan G protein-coupled receptor APJ agonist, with an EC50 of 20 nM. Apelin-36(human) shows high affinity to human APJ receptors expressed in HEK 293 cells (pIC50=8.61). Apelin-36 has been linked to two major types of biological activities: cardiovascular and metabolic. Apelin-36(human) inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ[1][2][3][4].
Molecular Weight:
4195.83
Purity:
98.01
CAS Number:
[252642-12-9]
Formula:
C184H297N69O43S
Target:
Apelin Receptor (APJ),HIV
Application Notes:
MCE Product type: Peptides
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