BMP-4 is a penetrating heparin-binding peptide with anti-inflammatory and anti-chondrogenic functions. In murine chondrocytes and macrophages, BMP-4 regulates the iNOS-IFN-IL6 signaling pathway to inhibit the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 in a dose-dependent manner, effectively suppressing inflammation and alleviating various arthritis symptoms[1].
Molecular Weight:
1308.52
CAS Number:
[1629625-47-3]
Formula:
C52H93N25O13S
Target:
COX,IFNAR,Interleukin Related
Application Notes:
MCE Product type: Peptides
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