ProTx-I, a venom toxin of the tarantula Thrixopelma pruriens, is a potent, selective CaV3.1 channel blocker with IC50 values of 0.2 µM and 31.8 µM for hCaV3.1 and hCaV3.2 respectively. ProTx-I is also a potent blocker for voltage-gated Na+ channels and inhibits KV 2.1 channels[1][2].
Molecular Weight:
3988.00
CAS Number:
[484598-35-8]
Formula:
C171H245N53O47S6
Target:
Calcium Channel,Potassium Channel,Sodium Channel
Application Notes:
Peptides
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