CALP2 is a calmodulin (CaM) antagonist ( (Kd of 7.9 µM)) with high affinity for binding to the CaM EF-hand/Ca2+-binding site. CALP2 inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca2+ concentrations. CALP2 potently inhibits of adhesion and degranulation. CALP2 is also a strong activator of alveolar macrophages[1][2][3][4].
Molecular Weight:
1357.70
CAS Number:
[261969-04-4]
Formula:
C68H104N14O13S
Target:
Calmodulin
Application Notes:
Peptides
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