DTS-108 is a prodrug of SN38 (HY-13704) (a Topoisomerase I inhibitor). DTS-108 is a conjugate generated by linking SN38 to a human oligopeptide via an esterase sensitive cross-linker. DTS-108 exhibits anti-tumor activity against colorectal, lung, and mammary cancer[1][2].
Molecular Weight:
3170.80
CAS Number:
[951792-83-9]
Formula:
C145H233N43O33S2
Target:
Peptide-Drug Conjugates (PDCs),Topoisomerase
Application Notes:
Peptides
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