MOTS-c (mouse) is a mitochondrial-derived polypeptide that can be used to regulates pancreatic cell function. MOTS-c (mouse) reduces insulin secretion and expression in INS-1E cells, and enhances glucagon secretion and expression in alphaTC-1 cells. MOTS-c (mouse) decreases the apoptosis in INS-1E and alphaTC-1. MOTS-c (mouse) counteracts diet-induced obesity and insulin resistance through AMPK activation[1].
Molecular Weight:
1446.73
Purity:
99.23
Formula:
C69H99N13O17S2
Target:
AMPK,Apoptosis
Application Notes:
Peptides
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