omega-Agatoxin TK, a peptidyl toxin of the venom of Agelenopsis aperta, is a potent and selective P/Q type Ca2+ channel blocker. omega-Agatoxin TK inhibits the high K+ depolarisation-induced rise in internal Ca2+ in cerebral isolated nerve endings with an IC50 of of 60 nM. omega-Agatoxin TK has no effect on L-type, N-type, or T-type calcium channels[1][2][3].
Molecular Weight:
5273.02
Purity:
99
CAS Number:
[158484-42-5]
Formula:
C215H337N65O70S10
Target:
Calcium Channel
Application Notes:
MCE Product type: Peptides
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