GNQWFI, an anti-Flt1 peptide, is a VEGFR1-specific antagonist. GNQWFI blocks the interaction of VEGFR1 with various VEGFR1 ligands, such as VEGFA, VEGFB, and placental growth factor (PIGF) and inhibits VEGF-induced endothelial cell migration and tube formation. GNQWFI is promising for research of cancer, asthma, and other ocular diseases[1].
Molecular Weight:
763.84
Purity:
99.45
CAS Number:
[853995-60-5]
Formula:
C37H49N9O9
Target:
VEGFR
Application Notes:
Peptides
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