Tkip is a JAK2 specific inhibitor. Tkip can bind the JAK2 autophosphorylation site, inhibit the JAK2 autophosphorylation and the phosphorylation of the IFN-gamma receptor subunit IFNGR-1. Tkip inhibits the antiviral activity of IFN-gamma and the expression of MHC Class I molecules. Tkip can be used to study the IFN-gamma signaling pathway[1].
Molecular Weight:
1684.03
CAS Number:
[716361-65-8]
Formula:
C93H118N16O14
Target:
JAK,MHC
Application Notes:
Peptides
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