KRL74 is a cyclic peptide inhibitor for interaction between the p6 domain of the HIV Gag protein and the UEV domain of the human TSG101 protein(p6/UEV) with an IC50 of 5.44 µM and a Kd of 11.9 µM. KRL74 inhibits the budding process of HIV from host cells with an IC50 of 2 µM in virus-like particle (VLP) budding assay[1].
Molecular Weight:
981.53
CAS Number:
[2423969-43-9]
Formula:
C50H61ClN10O9
Target:
HIV
Application Notes:
Peptides
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