cMCoFx1 is a potent and selective FXIIa cyclic peptide inhibitor. cMCoFx1 has high binding affinity (KD: 900 pM) and inhibitory activity (Ki: 370 pM) for FXIIa. cMCoFx1 can effectively inhibit endogenous clotting pathways, and cMCoFx1 is stable in serum and non-cytotoxic[1].
Molecular Weight:
3612.12
CAS Number:
[2853605-24-8]
Formula:
C146H232N52O44S6
Target:
Factor Xa
Application Notes:
Peptides
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