HL2-m5 is the inhibitor for the interaction between sonic hedgehog/patched (Shh/PTCH1) with Kd of 170 nM for Shh. HL2-m5 inhibits activation of Hedgehog signaling pathway and transcription of Gli-controlled gene with an IC50 of 230 nM[1].
Molecular Weight:
1632.83
Purity:
98.06
CAS Number:
[2130846-15-8]
Formula:
C70H101N15O24S3
Target:
Hedgehog
Application Notes:
Peptides
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