CNI103 is a highly potent and metabolically stable cell-permeable peptide inhibitor of calcineurin. CNI103 selectively blocks the interaction between calcineurin and NFATc3 (KD=16 nM), thereby preventing NFATc3 activation in vitro and in vivo. CNI103 can be used to study acute respiratory distress syndrome (ARDS) and other inflammatory diseases[1].
Molecular Weight:
2565.80
CAS Number:
[2366279-86-7]
Formula:
C116H180Cl2N36O26
Target:
Phosphatase
Application Notes:
Peptides
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