BRP is a 12-peptide derived from BRINP2 that can cross the blood-brain barrier. BRP induces the central activation of FOS in neuronal cells via the cAMP-PKA-CREB signaling pathway. BRP exerts anorectic and anti-obesity effects without triggering nausea or aversive responses. The action of BRP is independent of the leptin, GLP-1 receptor and melanocortin 4 receptor pathways. BRP is applicable to obesity-related research[1].
Molecular Weight:
1540.88
Purity:
95.15
Formula:
C68H117N25O14S
Target:
AP-1,PKA
Application Notes:
MCE Product type: Peptides
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