VSLRGDTRG is a synthetic peptide containing the RGD motif from cadherin 17 (CDH17), which binds to alpha2beta1 integrin and activates its signaling pathway. VSLRGDTRG promotes the high-affinity conformational change of beta1 integrin through the RGD motif, enhancing cell adhesion and phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. VSLRGDTRG can be used in research on cancers expressing CDH17, such as colon cancer and pancreatic cancer[1][2].
Molecular Weight:
960.05
CAS Number:
[2027476-29-3]
Formula:
C38H69N15O14
Target:
ERK,FAK,Integrin
Application Notes:
Peptides
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