GIP (22-51) human (Glucose-dependent Insulinotropic Peptide (22-51) human) is a potent proatherosclerotic peptide hormone consisting of 30 amino acids. GIP (22-51) human can activate the NF-kappaB signaling pathway, promote the expression of MMP-8, and induce the expression of proinflammatory and proatherosclerotic proteins. GIP (22-51) human can also increase the level of intracellular free Ca2+ in THP-1-induced macrophages. GIP (22-51) human can be used in the research of atherosclerosis[1].
Molecular Weight:
3181.56
CAS Number:
[957470-49-4]
Formula:
C140H226N44O41
Target:
Calcium Channel,MMP,NF-kappaB
Application Notes:
Peptides
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