NK224 is a peptide-based radiotracer targeting human PD-L1, with dual-radionuclide (68Ga and 18F) labeling compatibility enabled by the NOTA chelator. NK224 exhibits high binding affinity to PD-L1, with an IC50 value of 2.45 nM. NK224 visualizes intrapatient tumor heterogeneity and dynamically monitors PD-L1 target occupancy during immunotherapy. NK224 can be used for the study of non-small cell lung cancer (NSCLC)[1].
Molecular Weight:
2241.48
Formula:
C104H145N25O29S
Target:
PD-1/PD-L1
Application Notes:
Peptides
* VAT and and shipping costs not included. Errors and price changes excepted
