Ac2-26 is the N-terminal peptide of annexin 1, and has anti-inflammatory activity. Ac2-26 induces a decrease in IKKbeta protein in lysosomes by chaperone-mediated autophagy (CMA). Ac2-26 ameliorates lung ischemia-reperfusion injury. Ac2-26 also inhibits airway inflammation and hyperresponsiveness in an asthma rat model[1][2][3][4].
Molecular Weight:
3089.43
Purity:
99.14
CAS Number:
[151988-33-9]
Formula:
C141H210N32O44S
Target:
Annexin A,NF-kappaB
Application Notes:
Peptides
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