SjDX5-53 is a selective TLR2 inducer derived from a 3 kDa peptide from Schistosoma japonicum eggs. SjDX5-53 inhibits inflammatory Th1 and Th17 responses by inducing tolerogenic dendritic cells (tolDCs) and promoting the generation of regulatory T cells (Tregs) and their suppressive capacity. SjDX5-53 is primarily used in the treatment of autoimmune and inflammatory diseases such as colitis and psoriasis[1].
Molecular Weight:
3223.50
CAS Number:
[2767993-73-5]
Formula:
C128H208N46O46S3
Target:
Toll-like Receptor (TLR)
Application Notes:
Peptides
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