LVTX-8 is a peptide toxin, exacted from Lycosa vittata. LVTX-8 has potent anticancer and and anti-metastasis activities towards lung cancer with strong cytotoxicity. LVTX-8 significantly induces apoptosis and inhibits the proliferation, invasion and migration of lung cancer cells through P53 hypoxia pathways and integrin signaling. LVTX-8 significantly inhibits the tumor growth and metastasis in A549/H460 xenograft mice model[1].
Molecular Weight:
2849.46
CAS Number:
[2197957-07-4]
Formula:
C135H226N36O31
Target:
Apoptosis,Integrin,MDM-2/p53
Application Notes:
Peptides
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