YVPGP is an oligopeptide exacted from Anthopleura anjunae. YVPGP has a significant antitumor activity by mediating PI3K/AKT/mTOR signaling pathway. YVPGP arrests DU-145 cells in the S phase and induces apoptosis via mitochondrial and death receptor pathways (caspase3, 7, 8, 9). YVPGP effectively inhibits tumor growth in DU-145 xenografts mice model, promising for prostate cancer research[1].
Molecular Weight:
531.60
CAS Number:
[2095286-57-8]
Formula:
C26H37N5O7
Target:
Akt,Apoptosis,Bcl-2 Family,Caspase,mTOR,PI3K
Application Notes:
Peptides
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