CT20p is an anticancer peptide based on the C hydrophobic terminus of Bax. CT20p has a unique cytotoxic effect independent of full-length Bax, and can act on mitochondria, leading to fusion-like aggregation and mitochondrial membrane hyperpolarization. CT20p can reduce alpha5beta1 integrin levels and inhibit F-actin polymerization, thereby destroying the cytoskeleton and preventing cell attachment. CT20p can be used in the study of breast cancer[1].
Molecular Weight:
2176.66
CAS Number:
[1407967-57-0]
Formula:
C103H170N24O25S
Target:
Bcl-2 Family
Application Notes:
Peptides
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