[Ala92]-p16 (84-103) is a peptide derived from the p16CDKN2/INK4a (p16) tumor suppressor protein. [Ala92]-p16 (84-103) binds to both cdk4 and cdk6 and inhibits cdk4-cyclin D1 kinase activity in vitro (IC50: 1.5 µM). [Ala92]-p16 (84-103) blocks cell cycle progression through the G1 phase[1].
Molecular Weight:
2123.42
Purity:
98.16
CAS Number:
[189064-08-2]
Formula:
C93H155N31O26
Target:
CDK
Application Notes:
MCE Product type: Reference compound
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