Papiliocin is a potent peptide antibiotic with both anti-inflammatory and antibacterial activities. Papiliocin is primarily active against Gram-negative bacteria. Papiliocin exhibits strong anti-inflammatory activity against cell, exerting its anti-inflammatory activity by inhibiting the production of NO and the secretion of TNF-alpha and MIP-2. Papiliocin participates in the innate defense response mechanism by inhibiting the Toll-like receptor pathway and NF-kappaB. Papiliocin induces apoptosis in fungal cells and increases the total level of intracellular ROS. Papiliocin acts as an effective antiseptic peptide in sepsis models. Papiliocin is useful in anti-inflammatory and antibacterial research[1][3].
Molecular Weight:
4002.80
Formula:
C183H314N56O44
Target:
Antibiotic,Apoptosis,Bacterial,Fungal,Interleukin Related,NF-kappaB,NO Synthase,Reactive Oxygen Species (ROS),TNF Receptor,Toll-like Receptor (TLR)
Application Notes:
Peptides
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