PTD-DBM is a CXXC5-Dvl protein-protein interaction inhibitor and also a Wnt/beta-catenin pathway activator. PTD-DBM interferes with the Dvl-binding function of CXXC5, disrupts the negative feedback regulation of the Wnt/beta-catenin pathway, induces beta-catenin expression and nuclear translocation, and increases the production of type I collagen, alpha-smooth muscle actin and endothelin-1. PTD-DBM is applicable to studies related to androgenetic alopecia and skin wound healing[1][2][3].
Molecular Weight:
3082.64
Purity:
96.12
CAS Number:
[1609454-11-6]
Formula:
C124H225N61O28S2
Target:
Wnt,beta-catenin
Application Notes:
MCE Product type: Peptides
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