CIGB-552 is a cell-penetrating peptide with anti-tumor properties with the IC50 of 23 µM in H460 cells. CIGB-552 can increase the level of protein COMMD1. CIGB-552 significantly inhibits the NF-kappaB signaling pathway. CIGB-552 can promote apoptosis of the tumor cells. CIGB-552 can induce the accumulation of reactive oxygen species (ROS) in tumor cells. CIGB-552 has anti-inflammatory and anti-angiogenic effects. CIGB-552 can be used for the research of the lung cancer and colon cancer[1][2][3][4].
Molecular Weight:
2689.21
CAS Number:
[1630763-23-3]
Formula:
C131H198N38O24
Target:
Apoptosis,NF-kappaB,Reactive Oxygen Species (ROS)
Application Notes:
Peptides
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