Cyclosporin H is a selective and potent inhibitor of FPR-1 (formyl peptide receptor 1). Cyclosporin H, a viral transduction enhancer, increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Cyclosporin H displays an additive effect when combined with Rapamycin (HY-10219) or Prostaglandin E2 (HY-101952). Cyclosporin H lacks immunosuppressant activity of Cyclosporin A.
Molecular Weight:
1202.61
Purity:
99.87
CAS Number:
[83602-39-5]
Formula:
C62H111N11O12
Target:
Formyl Peptide Receptor (FPR)
Application Notes:
MCE Product type: Peptides
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