TI-16 is a peptide that targets beta-amyloid (Abeta) protein. TI-16 can cross the blood-brain barrier. TI-16 can increase the concentration of intracellular free CaM, thereby restoring calcium ion homeostasis and reducing Abeta toxicity. TI-16 can reduce the deposition of Abeta in the brain, improve neuronal pathology, inhibit cell apoptosis, and improve cognitive function in mice. TI-16 is commonly used in the study of Alzheimers disease[1].
Molecular Weight:
1639.73
CAS Number:
[659739-64-7]
Formula:
C72H102N24O21
Target:
Amyloid-beta,Apoptosis,CaMK
Application Notes:
MCE Product type: Peptides
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